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| L-型细菌诱导前后耐药质粒图谱及耐药性的对比研究 | |
| 引用本文： | 高娟丽,徐仓宝,苍金荣,苏宝风,魏宝贤. L-型细菌诱导前后耐药质粒图谱及耐药性的对比研究[J]. 现代检验医学杂志, 1998, 0(1) |
| 作者姓名： | 高娟丽 徐仓宝 苍金荣 苏宝风 魏宝贤 |
| 作者单位： | 陕西省人民医院检验科!710068(高娟丽，苍金荣，苏宝风)，西安医科大学分子生物研究室(徐仓宝)，卫生部临床检验中心(魏宝贤) |
| 摘 要： | 目的：比较诱导前后细菌质粒电泳图谱及耐药性的变化。方法：将携带有耐氨苄青霉素的基因的质粒转化入受体菌株大肠杆菌获得耐药菌，纸片法诱导形成L一型细菌。结果：诱导前后质粒电泳图谱相同，L－型细菌对破坏细菌细胞壁类抗生素敏感性降低，对干扰蛋白质和核酸合成的抗生素敏感性增强。 |
| 关 键 词： | L－型细菌 质粒 耐药性 |
Analysis R-plasmid electropherogram and resistance of E. cdi and it's L-form |
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| GAo Juan-li, XU Cang-Bao, CANG Jin-Rong, SU Bao-Feng, WEI Bao-Xian,. Analysis R-plasmid electropherogram and resistance of E. cdi and it's L-form[J]. Journal of Modern Laboratory Medicine, 1998, 0(1) | |
| Authors: | GAo Juan-li XU Cang-Bao CANG Jin-Rong SU Bao-Feng WEI Bao-Xian |
| Abstract: | Objective To analysis the difference of R-plasmid electropherogram and resistance between parental and it's L-form. Methods Trans form the R-plasmid to E. cdi,induces to produce it's L -form. Results The result shows that no difference between their plasmid electropherogarm, L-form possess more resistance to an-tibiotics that effect synthesize of protcin and nuclear acid. |
| Keywords: | L-form Plasmid Resistance |
| 本文献已被 CNKI 等数据库收录！ | |