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| 绍兴母乳中有机氯农药蓄积水平及趋势分析 | |
| 引用本文： | 周晓萍,潘国绍,韩建龙,徐小明,沈海涛,陈理,王若燕,王立媛,王晶. 绍兴母乳中有机氯农药蓄积水平及趋势分析[J]. 中国卫生检验杂志, 2012, 0(5): 953-954,959 |
| 作者姓名： | 周晓萍 潘国绍 韩建龙 徐小明 沈海涛 陈理 王若燕 王立媛 王晶 |
| 作者单位： | 浙江省绍兴市疾病预防控制中心;浙江省疾病预防控制中心 |
| 基金项目： | 绍兴市科技攻关计划重点项目(2008A23013) |
| 摘 要： | 目的:了解绍兴市正常居民母乳中有机氯的蓄积水平及动态变化趋势。方法:母乳经冷冻干燥后,加入同位素内标,经乙腈萃取,凝胶色谱净化,用气相色谱-质谱联用仪测定母乳中有机氯残留。结果:母乳中HCB中位值在检出限以下,总BHC、总DDT的中位值分别为698.7 ng/g脂肪和50.8 ng/g脂肪。母乳中BHC含量随着年龄增大而增高。1983-2009年绍兴市母乳中总BHC、总DDT分别下降99.8%和99.7%,1988年-2009年HCB下降90.0%。结论:绍兴市母乳中有机氯蓄积水平已处于相对安全水平。 |
| 关 键 词： | 母乳 有机氯农药 蓄积水平 |
Accumulative level and trend analysis of organochlorine pesticides in the breast milk in Shaoxing |
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| ZHOU Xiao-ping,PAN Guo-shao,HAN Jian-long,XU Xiao-ming,SHEN Hai-tao,CHEN Li,WANG Ruo-yan,WANG Li-yuan,WANG Jing. Accumulative level and trend analysis of organochlorine pesticides in the breast milk in Shaoxing[J]. Chinses Journal of Health Laboratory Technology, 2012, 0(5): 953-954,959 | |
| Authors: | ZHOU Xiao-ping PAN Guo-shao HAN Jian-long XU Xiao-ming SHEN Hai-tao CHEN Li WANG Ruo-yan WANG Li-yuan WANG Jing |
| Affiliation: | 1(1.Shaoxing Center for Disease Control and Prevention,Shaoxing 312071,China;2.Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou 310051,China) |
| Abstract: | Objective:To evaluate accumulative level and dynamics trend of organochlorine pesticides in the breast milk in Shaoxing.Methods: Breast milk was added 13C labeled internal standard after freeze-drying.Then the sample was extracted by acetonitrile,purified by gel permeation chromatography(GPC),and analyzed by gas chromatography coupled to mass Spectrometry under SIM mode.Results: The median of HCB was below the detection limit level.The geometrical mean levels of BHC and DDT residues were 698.7 ng/g lipid and 50.8 ng/g lipid respectively.BHC residue increased progressively together with advancing age.BHC and DDT residues decreased by 99.8% and 99.7% separately from 1983 to 2009.HCB residue reduced 90.0% from 1988 to 2009.Conclusion: The study showed that the breast milk in Shaoxing was relatively safe. |
| Keywords: | Breast milk Organochlorine pesticides Accumulative level |
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