石斛的化学成分及药理作用研究进展

目的综述石斛化学成分及药理作用的研究进展,为石斛的合理开发和临床应用提供理论参考。方法分别以“石斛”“Dendrobium”等为关键词在中国知网、PubMed等数据库中查询近十年关于石斛化学成分、药理作用及炮制工艺的文献,并选取具有代表性的进行整理综述。结果石斛的化学成分复杂,主要包括多糖类、生物碱类、黄酮类、菲类、联苄类、挥发油类、氨基酸及微量元素等;具有抗氧化、降尿酸、抗肿瘤、抗疲劳、降血糖、免疫调节等药理活性。结论随着研究者对石斛的活性成分及药理作用的研究深入,石斛在医药、保健等方面将有着广阔的应用前景。

Research progress on chemical constituents and pharmacological action of Dendrobium

Objective The research progress of Dendrobium chemical composition and pharmacological action was reviewed, which provided theoretical reference for the rational development and clinical application of Dendrobium.Methods Based on "Dendrobium" and other key words, the literature about chemical composition, pharmacological action and processing technology of Dendrobium in recent ten years was inquired in the database of CNKI, PubMed and so on, and representative literature were selected for review.Results The chemical components of Dendrobium are complex, mainly including polysaccharides, alkaloids, flavonoids, phenanthrene, benzenes, volatile oils, amino acids and trace elements, etc. It has the pharmacological activities of anti-oxidation, anti uric acid, anti-tumor, anti fatigue, hypoglycemia, immune regulation, etc.Conclusions With the further study of active components and pharmacological effects, Dendrobium will have a broad application prospect in medicine, health care and other aspects.