2型糖尿病患者抑郁情绪与糖化血红蛋白、血脂及其应对方式的研究

目的 探讨2型糖尿病患者抑郁情绪与糖化血红蛋白、血脂及其应对方式的关系.方法 根据Zung抑郁自评量表(Self-Rating Depression Scale,SDS)测定结果将73例2型糖尿病患者分为抑郁情绪组(n=31)和无抑郁情绪组(n=42),采用Zung焦虑自评量表(Self-Rating Anxiety Scale,SAS)进行验证考察.采用医学应对方式问卷(Medical Coping Modes Questionnaire,MCMQ)评定两组患者对疾病的应对方式,并比较两组患者糖化血红蛋白(HbA1c)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL C)水平的差异.结果 2型糖尿病有抑郁情绪组SAS标准分、MCMQ中屈服(resignation)方式分值高于无抑郁情绪组(P＜0.01),而两组间HbA1c、血脂水平及面对(confronce)、回避(avoidance)方式分值的差异均无统计学意义.结论 使用屈服应对方式的2型糖尿病患者更易合并抑郁情绪.

Association of depression with glycosylated hemoglobin,lipid metabolism and coping style in patients with type 2 diabetes mellitus

Objective To investigate the association of depression with glycosylated hemoglobin, lipid metabolism and coping style in patients with type 2 diabetes mellitus (DM). Methods A total of 73 patients with type 2 DM were divided into depression group (n=31) and non-depression group (n=42) according to the Results of Zung Self-Rating Depression Scale. The anxiety statuses were evaluated by Zung Self-Rating Anxiety Scale(SAS). The coping style was assessed by Medical Coping Modes Questionnaire (MCMQ). Moreover, the blood HbA1c, triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C) were also compared between the two groups. Results The SAS standard score and MCMQ score of resignation in the depression group were significantly higher than those in the non-depression group (P<0.01). The MCMQ score of confronce and avoidance, blood HbA1c, TG, TC, HDL-C, and LDL-C were not significantly different between the 2 groups. Conclusion It is suggested that type 2 DM patients with resignation coping style are more liable to have depression.