Bone Substitution and Augmentationin Trauma Surgery with a Resorbable Calcium Phosphate BoneCement

Background andPurpose:  

Synthetically manufactured bone substitute materials arewidely used to fill cancellous bone defects in fracturetreatment. By using these materials, complications occurringwith the harvesting of autologous bone such as inflammation,hemorrhage and pain are prevented. Ideally, afterosteointegration, the bone substitute resorbs, and completerestoration of bone architecture is achieved. Until now,clinical experience is limited to non-fully resorbable calciumphosphates, e. g., hydroxyapatite. Previous studies haverevealed a fully resorbable pure calcium phosphate, which isapplied in a paste form as a bone implant and results incomplete resorption and biocompatibility. The purpose of thisprospective, uncontrolled clinical study was to investigate thesafety and performance of this new resorbable bone substitutematerial.