| 急性化脓性扁桃体炎卫分证外周血Th1、Th2类细胞因子的表达及临床意义 |
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| 引用本文： | 刘旺华,周小青,刘建新,谢静,杨静宜.急性化脓性扁桃体炎卫分证外周血Th1、Th2类细胞因子的表达及临床意义[J].中华中医药学刊,2012(4):818-820. |
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| 作者姓名： | 刘旺华 周小青 刘建新 谢静 杨静宜 |
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| 作者单位： | 湖南中医药大学;湖南中医药大学附属第一医院 |
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| 基金项目： | 湖南省教育厅科研资助项目(08C621,10A093);湖南省高校创新平台开放基金资助项目(101C047) |
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| 摘 要： | 目的:研究急性化脓性扁桃体炎患者卫分证外周血Th1/Th2漂移变化。方法:通过流式细胞检测技术,对急性化脓性扁桃体炎患者卫分证和正常人外周血Th1/Th2细胞进行检测,采用ELISA法测定血清细胞因子IL-4和IFN-γ水平,并比较IFN-γ/IL-4比值。结果:与正常对照组比较,急性化脓性扁桃体炎卫分证组Th1、IFN-γ、Th1/Th2、IFN-γ/IL-4比值显著升高,差异有统计学意义(P0.05)。结论:急性化脓性扁桃体炎卫分证与Th1/Th2漂移存在相关性。
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| 关 键 词： | 扁桃体炎 T淋巴细胞亚群 Th1/Th2类细胞因子 流式细胞术 |
Study on Clinical Significance of Expressions of Th1/Th2 Cytokine in Wei-phase Syndrome of Acute Suppurative Tonsillitis |
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| LIU Wang-hua,ZHOU Xiao-qing,LIU Jian-xin,XIE Jing,YANG Jing-yi.Study on Clinical Significance of Expressions of Th1/Th2 Cytokine in Wei-phase Syndrome of Acute Suppurative Tonsillitis[J].Chinese Archives of Traditional Chinese Medicine,2012(4):818-820. |
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| Authors: | LIU Wang-hua ZHOU Xiao-qing LIU Jian-xin XIE Jing YANG Jing-yi |
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| Institution: | 1.Hunan University of Traditional Chinese Medicine,Changsha 410007,Hunan,China; 2.The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410007,Hunan,China) |
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| Abstract: | Objectives:To probe the drifting of Th1/Th2 in Wei-phase syndrome of Acute Suppurative Tonsillitis.Methods:Flowcytometry was used to dectect the Th1/Th2 cell in peripheral blood of the patients of Wei-phase syndrome and healthy people,the expressions of IL-4 and IFN-γ were detected by ELISA,and the ratio of IFN-γ/IL-4 was measured.Results:Compared with normal group,the number of Th1 and the contain of IFN-γ and the ratios of Th1/Th2 and IFN-γ/IL-4 of Wei-phase syndrome group increased significantly(P<0.05).Conclusion:The drifting of Th1/Th2 may play an important role during Wei-phase syndrome stage in Acute Suppurative Tonsillitis. |
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| Keywords: | tonsillitis T lymphocyte subsets Th1/Th2 cytokine flowcytometry |
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