银杏达莫注射液治疗糖尿病周围神经病变的临床研究

目的:通过对100例糖尿病周围神经病变(DPN)患者的临床研究,探讨银杏达莫针对DPN的临床治疗效果。方法:对照组患者口服甲钴胺片,研究组采用银杏达莫注射液联合甲钴胺片治疗。结果:研究组治疗总有效率明显高于对照组,数据经统计学比较具有显著差异(P0.05);两组患者治疗后正中神经、腓总神经的SNCV和MNCV均明显升高(P0.05),研究组治疗后SNCV和MNCV均明显高于对照组(P0.05);研究组不良反应发生率明显高于对照组,数据经统计学比较具有显著差异(P0.05)。结论:银杏达莫注射液与甲钴胺片联合应用对于DPN的临床治疗具有更好的疗效,且对神经传导速度的改善效果更加明显。

Clinical Study on Ginkgo Leaf Extract and Dipyridamole Injection Treating Diabetic Peripheral Neuropathy

Objective:Through clinical research on 100 cases of diabetic peripheral neuropathy(DPN),effects of ginkgo leaf extract and dipyridamole in DPN were observed.Methods:The patients of control group were given oral Mecobalamin tablets,treatment group used ginkgo leaf extract and dipyridamole injection combined with Mecobalamin tablets.Results:Total effective rate in treatment group was significantly higher than that in the control group,the data by statistical comparison was significant different(P<0.05);median nerve,common peroneal nerve of SNCV and MNCV of patients of two groups after treatment increased significantly(P<0.05),SNCV and MNCV of treatment group after treatment were significantly higher than those in control group(P < 0.05);the incidence of adverse reactions in treatment group were significantly higher than that in control group,the data by statistical comparison showed significant difference(P<0.05).Conclusion:Ginkgo leaf extract and dipyridamole injection and Mecobalamin tablets for the treatment of DPN has better curative effect,and the effect on the nerve conduction velocity improvement is more obvious.