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| 胃力康颗粒对实验性胃溃疡模型大鼠的影响 | |
| 引用本文： | 叶恒. 胃力康颗粒对实验性胃溃疡模型大鼠的影响[J]. 北方药学, 2012, 9(6): 30-31 |
| 作者姓名： | 叶恒 |
| 作者单位： | 福建南安市医院内科,南安,362300 |
| 摘 要： | 目的:观察胃力康颗粒对实验性胃溃疡大鼠的影响,探讨胃力康颗粒对实验性胃溃疡大鼠溃疡愈合的作用。方法:制备大鼠胃溃疡模型,大鼠随机分成正常组、模型组、法莫替丁对照组和胃力康治疗组,术后连续给药7d,测定大鼠血清中一氧化氮(NO)、超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量。结果:与模型组比较,胃力康组能显著提高大鼠血清中NO和SOD含量,降低MDA的含量,差异均有统计学意义(P<0.05)。结论:胃力康对大鼠胃溃疡的保护性治疗作用,其机制可能与提高血清NO和SOD含量,降低MDA含量有关。 |
| 关 键 词： | 胃力康 胃溃疡 NO SOD MDA |
Effect of Welikang on gastric ulcer induced by acetic acid in rats |
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| Ye Heng. Effect of Welikang on gastric ulcer induced by acetic acid in rats[J]. BEIFANG YAOXUE, 2012, 9(6): 30-31 | |
| Authors: | Ye Heng |
| Affiliation: | Ye Heng(Department of Internal Medicine of Nanan City Hospital,Nanan,Fujian,362300) |
| Abstract: | Objective:To investigate the therapeutic action of Welikang on ulcer healing in rats with experimental gastric ulcer.Methods:The rat gastric ulcer induced by acetic acid was selected and the content of NO,SOD and MDA were determined after perstetur drug gastric was injected.Results:The content of NO and SOD were increased significantly,and the content of MDA was decreased significantly in the Welikang group compared with those of model group.Conclusions:Welikang can increase the content of NO and SOD and decrease the content of MDA in serum,which may be the one basis of the mechanism to accelerate ulcer healing. |
| Keywords: | Welikang Gastric ulcer NO SOD MDA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |