| 二巯基丙磺酸钠治疗毒鼠强中毒的临床研究 |
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| 引用本文： | 谢玉增.二巯基丙磺酸钠治疗毒鼠强中毒的临床研究[J].中国医药指南,2011,9(23):189-190. |
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| 作者姓名： | 谢玉增 |
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| 作者单位： | 安徽省芜湖市第二人民医院儿科,安徽,芜湖,241000 |
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| 摘 要： | 目的探讨二巯基丙磺酸钠(Na-DMPS)治疗毒鼠强(Tetramine)中毒的临床效果及作用机制。方法应用Na-DMPS静脉或肌内注射治疗毒鼠强中毒,剂量因人而异。结果应用Na-DMPS治疗毒鼠强中毒的病例均取得良好的疗效,没有发现任何毒副作用。结论毒鼠强能阻断中枢神经系统的γ-氨基丁酸(GABA)受体而引起惊厥,Na-DMPS能通过多种机制影响GABA受体,降低惊厥发作的程度,值得临床医师试用。
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| 关 键 词： | 毒鼠强 二巯基丙磺酸钠 γ-氨基丁酸 |
Study Mechanics of Patient of Tetramine Toxicity Been the Rapied by Sodium Dimercaptopropanesulfonate |
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| XIE Yu-zeng.Study Mechanics of Patient of Tetramine Toxicity Been the Rapied by Sodium Dimercaptopropanesulfonate[J].Guide of China Medicine,2011,9(23):189-190. |
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| Authors: | XIE Yu-zeng |
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| Institution: | XIE Yu-zeng(Department of Pediatrics,Wuhu Second People's Hospital,Wuhu 241000,China) |
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| Abstract: | Objective To study mechanics of patient of tetramine toxicity been therapied by Na-DMPS.Method Who were tyerapied were concluded.Results Indicated that using Na-DMPS was appropriate without any by-actions.Conclusion And studies show that tetramine could insulate the receptor of GABA of central nerval system(CNS),then render convulsion,while Na-DMPS could lighten the degree of convulsion by influencing the receptor of GABA,but the mechanics are worth probing,and the method is worth popularizing. |
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| Keywords: | Tetramine Sodium dimercaptopropanesulfonate（Na-DMPS） Acid γ-aminobutyric（GABA） |
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