超声波探测系统模拟肠内容物感知神经的初步研究

为研究超声波对不同状态的肠内容物的辨别作用,以便为智能人工肛门的研制打下基础,本实验利用由MLU02-212型超声波气泡探测仪改装成的超声波探测系统分别测量20只新西兰兔近结肠远端10cm肠管内固体、流体、气体和空虚状态时的电压信号,分析不同状态肠内容物所表现的电压信号变化是否有显著性差异。实验结果表明:(1)近结肠内固体、流体、气体、空虚状态所造成的电压信号变化差异性显著(P=0.000);(2)多重比较各个不同状态之间电压信号差异性显著(P=0.000);(3)四种信号强度之间存在信号"不重叠区域"。本实验结果提示透射式超声波探测系统具有分辨不同肠内容物的作用,选用超声波探测肠内容物的方法可能为研究"人工肠内容物感知神经"的有效方法之一。

Preliminary study on simulating sensory nerves of intestinal contents using ultrasound detecting system

Successful assessing intestinal lumen content with ultrasound signals might lay a strong basis for the development of the artificial anal sphincter. In the present study, we utilized a modified MLU02-212 ultrasonic gas bubble detector to test the distal part of proximal colon in each rabbit, for the group of twenty healthy New Zealand rabbits. Voltage signals of solid, liquid, gas and empty content of the lumen were collected and compared. The results indicated that there were significant differences among the voltage signals in the 4 conditions (P = 0.000), respectively. Multiple comparison showed significant differences existed in any pair of the four conditions (P = 0.000). Three signal non-overlapping regions existed in these 4 conditions. Thus it seemed that ultrasound could be utilized to distinguish various contents inside the intestinal lumen and could act as "artificial sensory nerve".