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肠道病毒71型引起手足口病的发病机制
引用本文:尤俊斌,苏郑明. 肠道病毒71型引起手足口病的发病机制[J]. 医学研究生学报, 2012, 25(8): 876-878
作者姓名:尤俊斌  苏郑明
作者单位:汕头大学医学院生物化学与分子生物学教研室,汕头,515041
基金项目:广东省大学生创新实验项目,汕头大学医学院杰出大学生科研基金
摘    要:
手足口病(hand,foot and mouth disease,HFMD)是由肠道病毒引起的传染病。其中肠道病毒71型(enterovirus71,EV71)属于人类肠道病毒。近30年来EV71感染在亚太地区每2~3年暴发1次。EV71是手足口病的主要病原体,其详尽发病机制目前尚不清楚。文中综述EV71感染累及中枢神经系统,引起心肌炎和肺水肿的发病机制研究现状。

关 键 词:手足口病  肠道病毒71型  发病机制

Pathogenesis of hand,foot and mouth disease caused by Enterovirus 71
YOU Jun-bin , SU Zheng-ming. Pathogenesis of hand,foot and mouth disease caused by Enterovirus 71[J]. Bulletin of Medical Postgraduate, 2012, 25(8): 876-878
Authors:YOU Jun-bin    SU Zheng-ming
Affiliation:checking(Department of Medical College of Shantou University,Shantou 515041,Guangdong,China)
Abstract:
Hand,foot and mouth disease(HFMD) is an infectious disease caused by intestinal virus.Enterovirus 71(EV71)is one of the most common strains of human enterovirus.In recent 30 years,EV71 infection outbreaks every 2 to 3 years in the Asia-Pacific Regions,and EV71 is the main pathogen causing HFMD.The pathogenesis is still less understood.The studies on pathogenesis of EV71 infection that involves in central nervous system,leads to myocarditis or pulmonary edema are reviewed.
Keywords:Hand,Foot and Mouth Disease  Enterovirus 71  Pathogenesis
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