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| WT1基因在白血病中的表达及其临床意义 | |
| 引用本文： | 聂波,杨绵本. WT1基因在白血病中的表达及其临床意义[J]. 昆明医学院学报, 2003, 24(4): 100-103 |
| 作者姓名： | 聂波 杨绵本 |
| 作者单位： | 昆明医学院第一附属医院血液内科,昆明,650032 |
| 摘 要： | WT1基因最早作为Wilms瘤的抑癌基因被发现．近年来发现它在造血组织中也有表达，并与白血病的发生、发展及预后有关．由于WT1在白血病中的表达有一定规律性，故可能成为微小残留白血病的检测标志．现就WT1基因在白血病中的表达及其临床意义作一综述． |
| 关 键 词： | WT1基因 白血病 基因表达 抑癌基因 预后 |
| 文章编号： | 1003-4706(2003)04-0100-04 |
| 修稿时间： | 2003-08-10 |
Expression of Wilms'''' Tumor Gene (WT1) in Leukemias and Its Significance |
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| NIE Bo,YANG Mian-bun. Expression of Wilms'''' Tumor Gene (WT1) in Leukemias and Its Significance[J]. Journal of Kunming Medical College, 2003, 24(4): 100-103 | |
| Authors: | NIE Bo YANG Mian-bun |
| Abstract: | WT1 was initially identified as the tumor suppressor gene for Wilms' tumor. Recently it was found that WT1 was expressed in hematopoietic tissue, and played a role in leukemogenesis, and the development and prognosis of leukemia. Since WT1 expression is a typical feature of leukemia, it can be a marker of MRD. |
| Keywords: | Wilms' tumor Gene Leukemia Minimal residual disease Prognosis |
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