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煤矽肺患者血中微量元素和脂质过氧化的改变
引用本文:李成,刘志宏,朱玲勤. 煤矽肺患者血中微量元素和脂质过氧化的改变[J]. 中国公共卫生, 2001, 17(5): 408-409
作者姓名:李成  刘志宏  朱玲勤
作者单位:1. 宁夏回族自治区劳动卫生职业病防治所银川750004
2. 宁夏医学院
摘    要:
目的 了解煤矽肺患质过氧化水平。方法 检测煤矽肺患血清中微量元素Cu、Zn含量及MDA、SOD和GSH的水平。结果 煤矽肺患血清中Cu、Zn、MDA、SOD明显高于对照组,GSH明显低于对照组。煤矽肺患工龄、期别不同,其脂质过氧化水平也不同。吸烟可促进脂质过氧化发生改变。结论 煤尘可引起接触人群脂质过氧化紊乱。脂质过氧化可能是影响煤矽肺发生、发展的主要因素之一。

关 键 词:煤矽肺 微量元素 脂质过氧化 吸烟
文章编号:1001-0580(2001)05-0408-02
修稿时间:2001-01-07

The Alteration of theLipid Peroxidative Levels of Coal Workers'Pneumoconiosis Patients
LI Cheng,et al.. The Alteration of theLipid Peroxidative Levels of Coal Workers'Pneumoconiosis Patients[J]. Chinese Journal of Public Health, 2001, 17(5): 408-409
Authors:LI Cheng  et al.
Affiliation:Yinchuan 750004
Abstract:
Objective To study the lipid peroxidative levels of coal workers' pneumoconiosis(CWP)patients.Methods The content of the trace elements Cu and Zn in serum and the levels of MDA,superoxide Dismutase(SOD) and MDA were determined.Results The content of Cu,Zn in serum and the level of MDA and SOD activities of CWP were higher than that of control group,the GSH content of CWP was lower than that of control group.When the length of service and the stages of pneumoconiosis of CWP were change,the contents of trace elements and the lipid peroxidative levles were change too.Smoking could affect the lipid peroxidative leves.Conclusion This study suggested that coal dust nigth cause metabolic disorder in term of lipid peroxidation on exposed workers,lipid peroxidation may be a main effective factor to coal workers' penumoconiosis.
Keywords:coal workers' penumoconisis  trace element  lipid peroxidation  smoking
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