Left frontotemporal hyperperfusion in a patient with post-stroke mania |
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| Authors: | Mimura Masaru Nakagome Kazuyuki Hirashima Natsuko Ishiwata Hiroshi Kamijima Kunitoshi Shinozuka Akira Matsuda Hiroshi |
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| Affiliation: | Department of Neuropsychiatry, Showa University School of Medicine, 1-5-8 Hatanodai, Tokyo 142-8666, Japan. mimura@med.showa-u.ac.jp |
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| Abstract: | ![]()
A 78-year-old housewife with major depression developed a right-sided infarction in the territory of the middle cerebral arteries, followed by acute post-stroke mania. Comparison between pre- and post-stroke SPECT scans demonstrated a unique pattern of left orbitofrontal hyperperfusion with extensive right frontal hypoperfusion. A functional imbalance between right and left orbitofrontal cortices may be important in mania. |
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