静脉注射胺碘酮治疗急性心肌梗死伴室性心动过速和心室纤颤的临床效果观察

目的探讨静脉注射胺碘酮治疗急性心肌梗死伴持续性室性心动过速(室速)和心室纤颤(室颤)的临床效果。方法选取2008年3月至2010年5月因急性心肌梗死伴持续性室速和室颤于武警辽宁省总队医院急诊科进行治疗的患者96例作为研究对象,随机分为观察组患者48例(采用静脉注射胺碘酮治疗),对照组患者48例(采用利多卡因治疗),分析两组患者的治疗情况及不良反应。结果观察组有效率为95.8%,复发率为2.1%,不良反应发生率为8.3%,与对照组比较差异均有统计学意义(χ2=7.648,6.875,8.465,P<0.05)。结论静脉注射胺碘酮能够有效治疗急性心肌梗死伴持续性室速和室颤,具有临床治疗效果显著、不良反应较低的优点。

Clinical Effect Observation on Intravenous Injection of Amiodarone for the Treatment of Acute Myocardial Infarction with Sustained Ventricular Tachycardia and Ventricular Fibrillation

Objective To discuss the clinical effects of intravenous injection of amiodarone for the treatment of acute myocardial infarction with sustained ventricular tachycardia(VT)and ventricular fibrillation(VF).Methods From March,2008 to May 2010,96 patients with acute myocardial infarction with sustained ventricular tachycardia and ventricular fibrillation from Emergency Department of the Hospital of Liaoning Armed Police Corps were selected as objects.They were randomly divided into observation group and control group.Observation group(intravenous injection of amiodarone treatment group,n=48) and control group(lidocaine treatment group,n=48).A retrospective analysis on treatment situations and adverse reactions was made.Results In observation group,the efficiency rate was 95.8%,relapse rate was 2.1%,incidence of adverse reactions was 8.3%,which were statistically significantly different compared with the control group(χ2=7.648,6.875,8.465,P<0.05).Conclusion Intravenous injection of amiodarone for the treatment of acute myocardial infarction with sustained ventricular tachycardia and ventricular fibrillation has the advantages of obvious clinical effects and lower incidence of adverse reactions.