Herpes simplex virus type 2 DNA detected in cerebrospinal fluid of 9 patients with Mollaret's meningitis |
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| Authors: | M. Jensenius,B. Myrvang,G. Stø rvold,A. Bucher,K. B. Hellum,A.-L. Bruu |
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| Affiliation: | Department of Internal Medicine, Aker University Hospital;Department of Infectious Diseases;Microbiological Department, Ullevål University Hospital, Oslo;Department of Internal Medicine, Bærum Hospital, Bærum;Department of Infectious Diseases, Akershus Central Hospital, Nordbyhagen;Department of Virology, National Institute of Public Health, Oslo, Norway |
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| Abstract: | We present clinical and virological data on 9 patients, 7 women and 2 men aged 31–56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis. Six patients had no history of genital herpes. Only 1 patient was offered prophylactic antiviral treatment during the study period (45 months). |
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| Keywords: | Herpes simplex virus type 2 aseptic meningitis polymerase chain reaction |
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