原发性中枢神经系统淋巴瘤的影像学表现

目的：探讨原发性中枢神经系统淋巴瘤的影像学表现，以提高影像诊断水平。方法回顾性分析25例经病理证实的原发性中枢神经系统淋巴瘤的CT、MRI等影像学资料。结果单发16例，多发9例，共有39个病灶，幕上35个病灶，幕下4个病灶。单发病灶多位于脑白质深部，多发病灶常位于脑实质中线部位及大脑凸面。肿瘤在CT表现呈稍高密度，病灶T1WI多呈等或稍低信号，T2WI多呈等或稍高信号，DWI多呈高信号。增强扫描多呈明显均匀强化，少数呈斑片状强化；瘤周可见不同程度的水肿。结论原发性中枢神经系统淋巴瘤的CT、MRI表现具有一定特征性，结合临床并综合其影像学表现，可提高其诊断准确率。

The imaging features of primary lymphoma in central nervous system

Objective To explore the imaging features of primary lymphoma in central nervous system so as to improve the diagnostic accuracy of imaging .Methods A retrospective analysis of imaging findings was performed on 25 cases with pathologically confirmed central nervous system lymphoma .Features of CT or MRI appearances of the tumors were stud-ied .Results On CT ,MRI imaging ,single lesions were found in 16 cases and multiple ones in 9 .The single lesions were commonly located in deep white matter ,while these multiple lesions were more commonly located in midline structure and convex regions of brain hemisphere .These lesions were isointensity or slightly hyperintenity on CT images ,and isointense or slightly hypo-intense on T1 weighted images ,and isointense or slightly hyper-intense on T2 weighted images .The le-sions were hyperintensity on diffusion weighted image .In contrast enhancement ,those lesions displayed in a intense and homogeneous pattern .Different edema existed around these lesions .Conclusion The imaging findings of primary lympho-ma in central nervous system have some characteristics ,its diagnostic accurate rate can be improved by considering both the CT and MRI features and the patient’s clinical information .