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| 豚鼠耳蜗心钠素免疫反应阳性颗粒的超微结构观察 | |
| 引用本文： | 陈合新,王锦玲. 豚鼠耳蜗心钠素免疫反应阳性颗粒的超微结构观察[J]. 临床耳鼻咽喉头颈外科杂志, 1998, 12(9): 415-417 |
| 作者姓名： | 陈合新 王锦玲 |
| 作者单位： | [1]第一军医大学南方医院耳鼻咽喉科 [2]第四军医大学西京医院耳鼻咽喉科 |
| 摘 要： | 为进一步研究心钠素免疫反应（ＡＮＰ－ＩＲ）产物在耳蜗组织中的超微结构，探讨其分泌的形式，采用航向电镜对耳蜗血管纹ＡＮＰ－ＩＲ阳性颗粒的超微结构进行观察。结果表明，ＡＮＰ－ＩＲ阳性颗粒在细胞核两端分布较密集；其有两种状态，即储存颗粒和分泌颗粒。阳性颗粒有明显的限制膜，有些颗粒部分限制膜不完整，揭示：ＡＮＰ阳性颗粒分泌是以限制膜破裂而不是以胞吐的形式释放。 |
| 关 键 词： | 心钠素 超微结构 耳蜗 生理 |
The study of ultrastructure of atrial natriuretic peptides immunoreactive in cochlear of guinea pigs |
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| Chen Hexin, Wang Jinling. The study of ultrastructure of atrial natriuretic peptides immunoreactive in cochlear of guinea pigs[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 1998, 12(9): 415-417 | |
| Authors: | Chen Hexin Wang Jinling |
| Affiliation: | Nanfang Hospital, First Military Medical University, Guangzhou 510515. |
| Abstract: | To further explore ultrastructure of atrial natriuretic peptides immunoreactive (ANP-IR) products in cochlear of guinea pig,and secretory type, ultrastructure of ANP-IR products of stria vascularis were studied with immunoelectronic ndcroscopy. The result idrited:ANPIR granules were seen in the cytoplasm,more obviously at the ends of the nucleus. There were twotypes of granule:storage and secretory granule. The study suggests that ANPs were secreted by rupture of restriction membrane,not by exocytosis secretion. |
| Keywords: | Atrial natriuretic peptides Ultrastructure Guinea pigs Cochlear |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |