| 甲磺酸培氟沙星滴鼻剂的制备及临床应用 |
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| 引用本文： | 周茂金 苏美英 等. 甲磺酸培氟沙星滴鼻剂的制备及临床应用[J]. 中国药师, 2001, 4(2): 106-107 |
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| 作者姓名： | 周茂金 苏美英 等 |
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| 作者单位： | 山东省泰安市中心医院,271000 |
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| 摘 要： | 目的：根据临床需要配制甲碘酸培氟沙星滴鼻剂。方法：采用紫外分光光度法测定含量，并进行稳定性试验、刺激性试验及临床疗效观察。结果：制剂制备工艺简单，含量测定方法简便可行，临床应用总有效率为95%，与对照组相比无显著差异（P＞0.05)。结论：本品对急慢性鼻炎、鼻窦炎疗效确切。
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| 关 键 词： | 甲磺酸培氟沙星 滴鼻剂 临床应用 紫外分光光度法 |
| 修稿时间： | 2000-07-21 |
Preparation and Clinical Use of Pefloxacin Nasal Drops |
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| Zhou Maojin,Su Meiying,Jing Weiguo. Preparation and Clinical Use of Pefloxacin Nasal Drops[J]. China Pharmacist, 2001, 4(2): 106-107 |
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| Authors: | Zhou Maojin Su Meiying Jing Weiguo |
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| Abstract: | Objectives: To prepare pefloxacin mesilate nasal drops according to clinical demand. Method:the content was determined by UV-spectrophotography. It's stability and irritant tests were conducted, and it's clinical efficacy was observed. Result: Technique of preparation was simple, the method for content determination was convenient and feasible. General effective rate was 95 % . but there was no statistically significant difference compared with control group( P > 0. 05). Conclusion: The preparation had obvious therapy efficacy for acute and chronic rhinits and naso sinusitis. |
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| Keywords: | Pefloxacin Nasal drops Clinical use |
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