| 抗氧化剂在肝病治疗中的循证医学证据 |
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| 引用本文： | 刘衡,陆伦根. 抗氧化剂在肝病治疗中的循证医学证据[J]. 胃肠病学, 2012, 17(8): 491-495 |
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| 作者姓名： | 刘衡 陆伦根 |
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| 作者单位： | 上海交通大学附属第一人民医院消化科 200080 |
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| 摘 要： | 研究表明氧化应激是多种肝病的共同特征。本文对常用抗氧化剂8-胡萝b素、维生素A、C、E和硒在肝病治疗中的循证医学证据进行了综述,发现无足够证据支持这些抗氧化剂对肝病患者有明显益处,没有任何一种抗氧化剂能增加慢性病毒性肝炎在停止治疗时的持续病毒学应答病例数。需开展更多临床研究以评价抗氧化剂用于肝病治疗的利弊。
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| 关 键 词： | 抗氧化剂 肝疾病 循证医学 |
Evidence-based Medicine Proofs of Antioxidants Supplementation for Liver Diseases |
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| LIU Heng , LU Lungen. Evidence-based Medicine Proofs of Antioxidants Supplementation for Liver Diseases[J]. Chinese Journal of Gastroenterology, 2012, 17(8): 491-495 |
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| Authors: | LIU Heng LU Lungen |
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| Affiliation: | . Department of Gastroenterology,Shanghai First People’ s Hospital,Shanghai Jiaotong University,Shanghai(200080) |
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| Abstract: | Previous studies demonstrated that oxidative stress is commonly associated with a number of liver diseases. We summarized the evidence-based medicine proofs of several frequently used antioxidants,includingβ-carotene,vitamin A,C,E and selenium in the treatment of liver diseases,and revealed that there were no sufficient evidences supporting the beneficial effects of these antioxidants on liver diseases,and no one of these antioxidants could increase the sustained virological response in patients with chronic viral hepatitis on cessation of treatment.More clinical studies are required for assessing the benefits and demerits of antioxidants supplementation for liver diseases. |
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| Keywords: | Antioxidants Liver Diseases Evidence-Based Medicine |
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