老年高血压病患者血压波动规律的临床研究

目的:探讨老年高血压病患者24小时血压的波动规律,指导临床用药。方法:运用无创袖带式动态血压监测仪监测50例老年高血压病患者(老年组)和50例中青年高血压病患者(中青年组)各项血压参数,并进行对比分析。结果:两组24小时平均收缩压、日间平均收缩压、夜间平均收缩压、收缩压负荷比较,差异具有显著统计学意义(P<0.05),但两组的24小时平均舒张压、日间平均舒张压、夜间平均舒张压、舒张压负荷比较,差异无统计学意义(P>0.05),两组血压昼夜节律变化比较,差异具有显著统计学意义(P<0.05)。结论:老年高血压病患者以收缩压升高为主,血压昼夜节律消失,且较中青年患者更具易变性和不稳定性。

Clinical Study on Fluctuations of Ambulatory Blood Pressure in Older Peoples with Hypertension

Objective:This thesis focuses on the fluctuation rules of 24 hours ambulatory blood pressure in older peoples with hypertension so as to guide Medication using in clinical practice.Methods:Using the non-invasive ambulatory blood pressure monitoring devices to measure blood pressure in 50 older people and 50 middle-aged people who suffered from hypertension,the data of ambulatory blood pressure were collected and compared between the two groups.Results:There were significant difference in average of 24 hours systolic blood pressure,average daytime systolic blood pressure,average daytime systolic blood pressure and systolic blood pressure load between the two groups(P<0.05),but there were no difference in 24 hours average diastolic blood pressure,daytime diastolic blood pressure,nocturnal diastolic blood pressure and diastolic blood pressure load between the two groups(P>0.05).Still there was significant difference in the day-night rhythm of blood pressure between the two groups(P<0.05).Conclusion:Compared with middle-aged patients,older people with hypertension present increased systolic blood pressure mainly and disappearance of day-night rhythm of blood pressure,their blood pressure have easily changeable and instable features