杨积武教授益气活血方治疗冠心病不稳定心绞痛气虚血瘀型临床观察

目的：探讨杨积武教授在治疗气虚血瘀型冠心病的经验方，验证其临床疗效。方法：按诊断标准选取42例患者并分为2组。2组患者除每天静点硝酸酯类药物外，治疗组每天服用益气活血方汤荆；对照组每天服用脂必妥片。观察期间禁止使用除硝酸甘油外其他治疗冠心病心绞痛的中西药物，共18天。结果：治疗组的心绞痛症状和硝酸甘油停减率总有效率均明显高于对照组。心电图疗效指标中，两组的总有效率无统计学意义。各例患者治疗后检查肝肾功能，均无明显变化。结论：本经验方与脂必妥之间除心电图疗效无明显差异外，其它指标均优于对照药。临床中可以随时根据患者的各种兼症加减应用，灵活多变，对肝功肾功也无明显的损害。

Treatment of Coronary Heart Disease and Unstable Angina of Qi- Deficiency and Blood-Stasis Pattern by Yiqi Huoxue Fang of Professor YANG Ji-wu

Objective:This experiment is aimed at identifying the clinical effects of experience formula of Pro.Yang in treatment of coronary heart disease of qi-deficiency and blood-stasis pattern.Methods:42 patients chosen as the diagnosis standard are randomly divided into two groups.In addition to intravenous drop of nitrates in both groups every day,the treatment group and the control group need to be taken Yiqi Huoxue Fang and Zhibituo,respectively.During the eighteen days of clinical observation,other drugs for treatment of CHDQB except nitrates,involving Chinese and Western medicine drugs,are prohibited.Results:In our studies,the symptom of angina in treatment group are improved effectively,and total effective rate after terminating Nitroglycerol in treatment group are significantly more than control group.No significant difference is observed between two groups in ECG.The liver and renal function of patients is not influenced after treatment.Conclusion:In clinic,we can flexibly coordinate the components of formula and dose of signal drug,moreover,the toxicity of liver and renal function is less after treatment.