肝非唾液酸糖蛋白受体显像与肝储备功能关系的研究

目的 探讨肝非唾液酸糖蛋白受体显像与肝储备功能关系。方法 对１９例肝硬变、门脉高压患者用＾９９ｍＴｃ标记ＮＧＡ（新半乳糖白蛋白）与ＡＳＧＰ－Ｒ（肝非唾液酸糖蛋白受体）结合法，观测肝受体显像；眼声多普勒观测肝血流的变化。结果 肝硬变组的ＭＲＩ、ＨＢＦ和ＡＢＣＨＥ均呈正相关，与总胆红素呈显著负相关。行肝切除贲门周围血管离断术７例，术后１周重新评估肝功能分级：术前肝功能Ⅰ级２例无变化；术前肝功能Ⅱ级５例

The Clinical Study of the Relations Between ASGP-R Developing and the Hepatic Reserve Function

Objective To investigate the relation between ASGP-R developing and the reserve function of hepar.Methods By the way of NGA and ASGP-R marked with 99m Tc in 19 cases of hepatocirrhosis and portal hypertension,than the variation of HBF was shown by ultrosound doppler.Results The MRI and HBF has positive correlation with ABchE,and has negative correlation with TBIL.Ligtion of pericardial blood vessel was done in 7 cases,then Liver function was reassessed one postoperative week.Two case did not vary,the function of hepar remained grade one.But two cases occured gread ascites,and hepatic function descended grade three from grade two.Conclusion From statistics and clinical observation,the way to determine HBF can be used to estimate the hepatic reserve function.