| CCE化疗联合胸腔内灌注平阳霉素、消瘤芥治疗肺癌伴胸腔积液51例临床观察 |
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| 引用本文： | 黄柱华,黄清广,王玲,秦凤展,丁永为.CCE化疗联合胸腔内灌注平阳霉素、消瘤芥治疗肺癌伴胸腔积液51例临床观察[J].中国肿瘤临床与康复,2001,8(1):35-36. |
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| 作者姓名： | 黄柱华 黄清广 王玲 秦凤展 丁永为 |
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| 作者单位： | 中国癌症研究基金会安徽省肿瘤康复医院 |
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| 摘 要： | 目的观察CCE化疗联合胸腔内灌注平阳霉素、消瘤芥治疗肺癌伴胸腔积液疗效。方法静脉化疗方案为CTX500～600mg/m
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| 关 键 词： | 肺癌伴胸腔积液 CCE方案 胸腔内灌注 平阳霉素和消瘤芥 |
| 文章编号： | 1005-8664(2001)01-35-02 |
| 修稿时间： | 2000年3月14日 |
The clinical investigation
on intrathoracic instillation of CCE c hemotherapy combined PMY and AT-1258 in 51 patients
with lung cancer accompaning hydrothorax |
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| HUANG Zhu hua,HUANG Qing guang,WANG Lin et al China Cancer Research Foundation Anhui Cancer Patient Rehabilitation Hospital,Bengbu.The clinical investigation
on intrathoracic instillation of CCE c hemotherapy combined PMY and AT-1258 in 51 patients
with lung cancer accompaning hydrothorax[J].Chinese Journal of Clinical Oncology and Rehabilitation,2001,8(1):35-36. |
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| Authors: | HUANG Zhu hua HUANG Qing guang WANG Lin China Cancer Research Foundation Anhui Cancer Patient Rehabilitation Hospital Bengbu [ |
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| Institution: | HUANG Zhu hua,HUANG Qing guang,WANG Lin et al China Cancer Research Foundation Anhui Cancer Patient Rehabilitation Hospital,Bengbu 233000 [ |
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| Abstract: | Objective To evaluate the effect of CCE chemother apy combined PYM and AT-1258 intrathoracic instillation on lung cancer accompan ied hydrothorax.Methods The chemotherapy remedy was CTX 500～60 0mg/m2 iv d1,CBP 400mg iv d1 and Vp-16 100mg iv d1～5.The therapeutic course was repeated at 4 weekly intervals.After drawing water,PYM 16mg and AT-1258 40 ～60mg and dexamethsome 10mg were injected into thoracic cavity,which was repeat ed at 7～10 days intervals.Results The effective rat e in patients with lung cancer and hydrothorax was 54.9% and 80.4%，respectively .The effective rate for mild、moderate and severe hydrothorax were 100%(12/12),8 2.1% (23/28)and 54.5%(6/11)(P<0.025).The side effects were arrest of bone marrow,dige stive tract reaction and alopecia.The survival time was 3～30 months,the median survival time was 12 months.Conclusions CCE chemotherapy combin ed PYM and AT-1258 intrathoracic instillation in the treatment of lung cancer a cco mpanied with hydrothorax is simple,effective,therefore it should be recommended. |
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| Keywords: | lung cancer accompanied with hydrothorax CCE remedy intrathoracic instillation PYM and AT 1258 |
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