|
|||||
|
|
| Heighten the Study on Factor Seven Activating Protease | |
| 引用本文： | 贺石林,陈方平,张广森,文志斌. Heighten the Study on Factor Seven Activating Protease[J]. 血栓与止血学, 2008, 14(3): 99-100 |
| 作者姓名： | 贺石林 陈方平 张广森 文志斌 |
| 摘 要： | Recent studies have showed that factor seven activating protease （FSAP） is a novel serine protease in human plasma. Immunoreactivity for FSAP has been observed in vascular endothelial cells, epithelial cells and macrophages but FSAP-specific mRNA expression only exists in the former two cells. FSAP has three epidermal growth factor （EGF） domains, a kringle domain and a serine protease domain. It circulates in the plasma as an inactive zymogen and undergoes autoactivation from a single chain to two chain enzyme form in the presence of polya-nionic macromolecules such as heparin and RNA. |
| 关 键 词： | 蛋白酶 上皮细胞 内皮细胞 核糖核酸 |
Heighten the Study on Factor Seven Activating Protease |
|
| HE Shi-lin,CHEN Fang-ping,ZHANG Guang-sen,WEN Zhi-bin. Heighten the Study on Factor Seven Activating Protease[J]. Chinese Journal of Thrombosis and Hemostasis, 2008, 14(3): 99-100 | |
| Authors: | HE Shi-lin CHEN Fang-ping ZHANG Guang-sen WEN Zhi-bin |
| Affiliation: | Xiangya Medica School/CSU,Ghangsha,410078 ,China |
| Abstract: | Recent studies have showed that factor seven activating protease (FSAP) is a novel serine protease in human plasma. Immunoreactivity for FSAP has been observed in vascular endothelial cells,epithelial cells and macrophages but FSAP-specific mRNA expression only exists in the former two cells. FSAP has three epidermal growth factor (EGF) domains,a kringle domain and a serine protease domain. |
| Keywords: | Factor Seven Activating Protease Protease Factor kringle domain epidermal growth factor epithelial macrophages mRNA expression vascular endothelial cells Immunoreactivity novel serine protease human plasma FSAP Recent studies |
| 本文献已被 维普 万方数据 等数据库收录！ | |