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| 山楂叶总黄酮分散片的研制 | |
| 引用本文： | 左安刚,周英,李俐,王慧娟. 山楂叶总黄酮分散片的研制[J]. 中国实验方剂学杂志, 2011, 17(11): 26-29 |
| 作者姓名： | 左安刚 周英 李俐 王慧娟 |
| 作者单位： | 1. 贵州大学生命科学学院,贵阳,550025;贵州大学中药天然药研发中心,贵阳,550025 2. 贵州大学生命科学学院,贵阳,550025;贵州大学中药天然药研发中心,贵阳,550025;贵州省中药材繁殖与种植工程实验室,贵阳,550025 |
| 基金项目： | 贵州省中药现代化科技产业研发专项，贵州省科技厅创新人才团队建设项目 |
| 摘 要： | 目的:筛选山楂叶总黄酮分散片的制剂处方。方法:以崩解时间为考察指标,考察不同种类的辅料及其用量,采用正交试验设计确定最佳处方。结果:分散片最优处方为16%山楂叶提取物,55%MCC,8%cCMC-Na,18%淀粉,1%硬脂酸镁,其崩解时间为(66±5)s。结论:研制的山楂叶总黄酮分散片处方合理,体外溶出度明显优于市售普通片剂,是值得开发的产品。 |
| 关 键 词： | 山楂叶总黄酮 分散片 制备 |
| 收稿时间： | 2010-12-23 |
Preparation of Hawthorn Leaves Total Flavonoids Dispersible Tablets |
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| ZUO An-gang,ZHOU Ying,LI Li and WANG Hui-juan. Preparation of Hawthorn Leaves Total Flavonoids Dispersible Tablets[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(11): 26-29 | |
| Authors: | ZUO An-gang ZHOU Ying LI Li WANG Hui-juan |
| Affiliation: | College of Life Sciences, Guizhou University, Guiyang 550025, China; Guizhou University Research and Development Center of Chinese Medicine and Natural Drugs, Guiyang 550025, China;College of Life Sciences, Guizhou University, Guiyang 550025, China; Guizhou University Research and Development Center of Chinese Medicine and Natural Drugs, Guiyang 550025, China; Guizhou Engineer Laboratory of Propagation and Cultivation on Traditional Chinese Medicinal Materials, Guiyang 550025, China;College of Life Sciences, Guizhou University, Guiyang 550025, China; Guizhou University Research and Development Center of Chinese Medicine and Natural Drugs, Guiyang 550025, China; Guizhou Engineer Laboratory of Propagation and Cultivation on Traditional Chinese Medicinal Materials, Guiyang 550025, China;College of Life Sciences, Guizhou University, Guiyang 550025, China; Guizhou University Research and Development Center of Chinese Medicine and Natural Drugs, Guiyang 550025, China; Guizhou Engineer Laboratory of Propagation and Cultivation on Traditional Chinese Medicinal Materials, Guiyang 550025, China |
| Abstract: | |
| Keywords: | hawthorn leaves total flavonoids dispersible tablets preparation |
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