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奥曲肽治疗食管静脉曲张破裂出血33例
引用本文:王学红 芦水福. 奥曲肽治疗食管静脉曲张破裂出血33例[J]. 青海医学院学报, 1996, 17(2): 100-101
作者姓名:王学红 芦水福
作者单位:Digestion group,Internal medicine,Qinghai Medical College Hospital
摘    要:
食管静脉曲张破裂出血临床常见,病死率高达28-60%,传统采用血管加压素和气囊压迫出血疗效欠佳。人工合成的八肽生物凶不长效类似物奥曲肽半衰期长,副作用少。一年余用奥曲肽33例肝硬化失代偿合并食管脉曲张破裂出血病人,上血率为84.8%,其中每日持续静滴0.4-0.6mg者与只静滴0.1-0.2mg者相比,前者止血率为100%,后者止血率为54.5%。

关 键 词:奥曲肽 食管静脉曲张 出血 治疗

33 CASES OF HEMARRHAGE OF RUPTURED ESOPHAGEAL VARICES TREATED WITH OCTREOTIDE
Fan Zhonglin,. 33 CASES OF HEMARRHAGE OF RUPTURED ESOPHAGEAL VARICES TREATED WITH OCTREOTIDE[J]. Journal of Qinghai Medical College, 1996, 17(2): 100-101
Authors:Fan Zhonglin  
Abstract:
Hemarrhage of ruptured esophageal varices is quite common in clinic and its mortality reached 28 - 60 %. Cthesic methods using vasopressin and air - pocket compression to control hemarrhsae are not well worked. Octreotide, an artifictal synthetic octapeptide and a long-acting analog of somatostatin,has a long half life and with no adverse effect. 33 cases of hepatocirrhosis decompensation with hemarrhage of ruptured esophageal varices were treated with octreotide and the hemastasis rate was 84. 8%. While using intravenous instillation of 0. 4 - 0. 6mg/day,the hemastasis rate was 100%;that of 0. 1 - 0. 2mg/dny,the hemastasis rate was 54. 5%.
Keywords:Octreotide  Hemarrhage of ruptured esophageal varices  Treatment
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