老年男性2型糖尿病患者认知功能损害的危险因素分析

目的调查老年男性2型糖尿病患者认知功能损害的危险因素,以预防该类患者功能损害的发生。方法目的性抽样选取2010年1-11月在解放军总医院内分泌科住院的老年男性2型糖尿病患者180例。采用简易生活量表(mini-mentalstate examinantion,MMSE)、临床痴呆量表(clinical dementia rating,CDR)、总体痴呆量表(global deterioate scale,GDS)对患者进行认知功能评价,根据认知功能评价将研究对象分为认知功能正常组与认知功能损害组。结果 180例患者中,认知功能正常48例,认知功能损害132例。年龄、脑卒中发生率、糖尿病病程、糖尿病微血管病变和低血糖反应发生率在两组老年男性2型糖尿病患者间差异有统计学意义(P<0.01)。结论老年男性2型糖尿病患者认知功能损害的发生率较高,与其相关的危险因素可能包括非糖尿病的相关因素和糖尿病的相关指标,故应做好相应的预防和护理工作,以提高其生活质量。

Analysis on Risk Factors of Cognitive Impairment in Elderly Man with Type 2 Diabetes

Objective To investigate the risk factors of cognitive impairment in elderly man with type 2 diabetes so as to provide basis for the corresponding prevention.Methods A total of 180 patients who met the enroll criterion were measured on their overall cognitive function by mini-mental state examination（MMSE）,clinical dementia rating（CDR） and global deterioate scale（GDS）.Then they were divided into normal group and cognitive impairment group.Results There were 48 patients in normal group and 132 in cognitive impairment group.Significant differences were observed on the cognitive impairment risk factors including age,the incidence of stroke,duration diabetes,diabetic microangiopathy and hypoglycemia（P〈0.01）.Conclusion The incidence of cognitive impairment elderly men with type 2 diabetes is high,and the risk factors included non-diabetes and diabetes-related indicators.Appropriate prevention and nursing work helps improve their quality of life.