| 脂联素与胰岛素抵抗、血液流变学改变及2型糖尿病大血管病变 |
| |
| 引用本文： | 张燕,孙辽. 脂联素与胰岛素抵抗、血液流变学改变及2型糖尿病大血管病变[J]. 现代保健, 2011, 0(29): 149-152 |
| |
| 作者姓名： | 张燕 孙辽 |
| |
| 作者单位： | [1]广东省珠海市第五人民医院,519055 [2]中山大学第五附属学院,519055 |
| |
| 基金项目： | 珠海市科技计划项目（2010B040102001） |
| |
| 摘 要： | 脂联素（adiponectin,APN）是脂肪细胞分泌的一种细胞因子,它是目前发现的唯一对人体有保护作用的脂源性激素,其浓度下降与糖尿病及其大血管病变密切相关。脂联素具有提高胰岛素敏感性,调节糖脂代谢,改善血液流变学,保护血管内皮和抑制动脉粥样硬化形成等作用,为防治2型糖尿病及糖尿病大血管病变提供新的药物治疗靶向。
|
| 关 键 词： | 脂联素 血液流变学 2型糖尿病 大血管病变 |
The study of adiponectin and insulin resistance, the change of hemorheology and macroangiovathy in tvue 2 diabet melitus |
| |
| ZHANG Yan,SUN Liao. The study of adiponectin and insulin resistance, the change of hemorheology and macroangiovathy in tvue 2 diabet melitus[J]. , 2011, 0(29): 149-152 |
| |
| Authors: | ZHANG Yan SUN Liao |
| |
| Affiliation: | . (The Fifth Hospital of Zhuhai, Zhuhai 519055, China) |
| |
| Abstract: | Adiponectin（APN）is an eytokine secreted by adipocyte,and it is the only lipogenic hormone which has protective efection on human. Concentration decrease of adiponectin has close relations with diabetes and the macrovascular compueation ot dtabetes. Adiponeetin has tunetion of cutting down the blood sugar level, improving insulin sensitivity, proteeting blood vesset endothelium and resisting the vascular sclerosis. It could provide new therapeutic target to prevent and treat type 2 diabetes and the macrovascular complication of diabetes. |
| |
| Keywords: | Adiponectin Hemorheology Type 2 diabete Macroangiopathy |
| 本文献已被 维普 等数据库收录！ |
|
