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| 治疗轻中度失眠症的安慰剂效应分析 | |
| 引用本文： | 敬攀,宋秀华,麻小莉,郑天生,付晔,唐闻捷,何金彩. 治疗轻中度失眠症的安慰剂效应分析[J]. 温州医学院学报, 2011, 41(2): 103-106 |
| 作者姓名： | 敬攀 宋秀华 麻小莉 郑天生 付晔 唐闻捷 何金彩 |
| 作者单位： | 1. 温州医学院附属第一医院,睡眠中心,浙江,温州,325000 2. 温州医学院,浙江,温州,325035 |
| 基金项目： | "十一五"国家科技支撑计划资助项目，国家高科技研究发展计划资助项目(863计划) |
| 摘 要： | 目的：了解治疗轻中度失眠症的安慰剂效应情况及影响此效应的相关因素。方法：运用与乌灵胶囊的外观、重量、气味和口味完全相同的安慰剂对轻中度失眠症受试者进行为期4周的治疗。以匹兹堡睡眠质量指数量表（PSQI）总分和WHO生存质量测定量表简表（WHOQOL-BREF）各领域分数的情况评价治疗效果。以PSQI总分降分率≥25%作为判定产生了安慰剂效应的标准,分析与安慰剂效应相关的因素。结果：与治疗前相比,治疗后PSQI总分平均减少（4.16±3.17）分,差异有统计学意义（P〈0.01）;WHOQOL-BREF各领域得分在治疗前后差异也有统计学意义（P〈0.01）。治疗前后,PSQI总分减分值与病程呈负性相关,与PSQI总分呈正性相关。对安慰剂效应的影响因素分析显示,病程≤6个月比〉6个月易出现安慰剂效应,文化程度越高越容易出现安慰剂效应。结论：治疗轻中度失眠症的安慰剂效应明显,安慰剂效应与病程、文化程度存在联系。 |
| 关 键 词： | 失眠 安慰剂 治疗 相关因素 |
Evaluation of correlated factors of placebo effects in adults with mild insomnia |
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| JING Pan,SONG Xiuhua,MA Xiaoli,ZHENG Tiansheng,FU Ye,TANG Wenjie,HE Jincai. Evaluation of correlated factors of placebo effects in adults with mild insomnia[J]. Journal of Wenzhou Medical College, 2011, 41(2): 103-106 | |
| Authors: | JING Pan SONG Xiuhua MA Xiaoli ZHENG Tiansheng FU Ye TANG Wenjie HE Jincai |
| Affiliation: | JING Pan*,SONG Xiuhua,MA Xiaoli,ZHENG Tiansheng,FU Ye,TANG Wenjie,HE Jincai.*Sleep Center,the First Affiliated Hospital of Wenzhou Medical College,Wenzhou,325000 |
| Abstract: | Objective: To evaluate the efficacy of placebo in adults with mild insomnia and factors correlated with the efficacy.Methods: Adults with mild insomnia were treated with placebo which was same as Wuling capsule for four weeks.The effect was evaluated by scores of Pittsburgh Sleep Quality Index(PSQI)and World Health Organization Quality Of Life-Brief(WHOQOL-BREF).If the score of PSQI descented more than 25%,it was thought that it had placebo effects.Used this standard,the factors correlated with placebo effe... |
| Keywords: | insomnia placebo effects treatment correlated factors |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |