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| 猴脑震荡时某些生化、生理指标的改变 | |
| 引用本文： | 吴桂荣,张云然,王玉清,由广兴. 猴脑震荡时某些生化、生理指标的改变[J]. 中华航空航天医学杂志, 1994, 0(1) |
| 作者姓名： | 吴桂荣 张云然 王玉清 由广兴 |
| 作者单位： | 北京航天医学工程研究所!100094 |
| 摘 要： | 观察了猴脑震荡时某些生化、生理指标的改变，为动物实验中脑震荡的判断提供依据。在动态加载机上对24只猴进行了头部冲击，另4只猴不进行冲击作为对照。依据有关临床诊断标准判别，冲击后8只猴发生了单纯性脑震荡，4只为脑震荡伴脑损伤。结果表明，发生了脑震荡的猴出现了暂短生理反射减弱或消失，呼吸和心率减慢，脑干神经细胞有尼氏体减少现象。脑震荡伴脑损伤猴脑脊液中检出红细胞和肌酸激酶脑型同功酶，单纯性脑震荡猴及无脑损伤猴均未检出。 |
| 关 键 词： | 脑震荡 脑脊髓液 肌酸激酶同工酶类 冲击损伤 |
Changes of some medical parameters in monkeys after brain concussion |
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| Wu Guirong, Zhang Yuran ,Wang Yuqing,et al.. Changes of some medical parameters in monkeys after brain concussion[J]. Chinese Journal of Aerospace Medicine, 1994, 0(1) | |
| Authors: | Wu Guirong Zhang Yuran Wang Yuqing et al. |
| Abstract: | In order to observe the biochemical,physiological and pathological changes in monkeysafter brain concussion, 24 monkeys underwent head impact of various intensity (2.0~ 3.0 kN) bymeans of the dynamic loader while 4 monkeys served as control. According to the clinical diagnosticstandatd,8 monkeys were judged to be concussion and 4 monkeys brain contusion. The results indicatedthat monkeys with signs of brain concussion revealed attenuation of physiological reflexes, slowing ofrespiration and heart rate and decrease of Nissl bodies in brain stem cells- RBC and CK-BB were found incerebrospinal fluid in monkeys with brain contusion,while in those with simple concussion as well as;controls, no RBC or CK-BB was found. This may be useful for assessing the degree of brain concussionin experimental animals. |
| Keywords: | Brain concussion Cerebrospinal fluid Creatine kinase isoenzymes Impact damage |
| 本文献已被 CNKI 等数据库收录！ | |