选择性激光小梁成形治疗开角型青光眼的疗效分析

目的 评价选择性激光小梁成形术治疗原发性开角型青光眼的疗效和安全性.方法 局部用药治疗的原发性开角型青光眼43只眼和高眼压症7只眼.使用Q开关倍频Nd:YAG激光实施180°小梁网激光照射.激光能量0.5～1.0 mJ,50～60个击射点.术后定期测量眼压和裂隙灯检查.随访期内仍然给予降眼压眼液.结果 平均随访8.6月(6～12月).术后所眼都有轻度前节炎症反应,3天后自然消退.术后继续使用降眼压眼液.A组(基线眼压17～24 mm Hg)和B组(基线眼压26～36 mm Hg)术后1、3、6、12月眼压下降幅度分别为30.1%、26.3%、25.6%、23.3%;和17%、21.5%、15%、10.9%,2组差异有显著性(P＜0.05).结论 SLT治疗开角青光眼的并发症是轻微的,降眼压的效果与术前眼压基线高低有关.

Abstract：

Objective To investigate the safety and efficacy of selective laser trabeculoplasty (SLT) in the treatment of open angle glaucoma.Methods Forty-three eyes with open-angle glaucoma and 7 eyes with ocular hypertension were treated withafrequency doubled Q-switched Nd:YAG laser.A total of 50～60 laser spots were placed over 180° of trabecular meshwork with energy levels ranging from 0.5 to 1.0mJ per pulse. Intraocular pressure measurement and slit lamp examination were regularly performed after laser surgery. Topical anti-glaucoma drug was given during the follow up period Results The follow up was 6～12 months (average 8.6 months). Slight inflammation of anterior chamber occurred in the all eyes, and disappeared 3 days later automatically. IOP reduction of group A (baseline IOP 17～24 mmHg) and groupB(baseline IOP 26-36 mmHg) was 30.1%, 26.3%, 25.6%,23.3%; and 17%, 21.5%. 15%, 10.9% at 1,3,6and 12 months, respectively. IOP reduction between two groups was significantly difference(P＜0.05). Conclusions Adverse effects of SLT for open angle glaucoma is a mild and temporary. Effect of lowing IOP isrelated to baseline pressure.

A retrospective study of selective laser trabeculoplasty in the treatment of primary open angle glaucoma

Objective To investigate the safety and efficacy of selective laser trabeculoplasty (SLT) in the treatment of open angle glaucoma.Methods Forty-three eyes with open-angle glaucoma and 7 eyes with ocular hypertension were treated withafrequency doubled Q-switched Nd:YAG laser.A total of 50～60 laser spots were placed over 180° of trabecular meshwork with energy levels ranging from 0.5 to 1.0mJ per pulse. Intraocular pressure measurement and slit lamp examination were regularly performed after laser surgery. Topical anti-glaucoma drug was given during the follow up period Results The follow up was 6～12 months (average 8.6 months). Slight inflammation of anterior chamber occurred in the all eyes, and disappeared 3 days later automatically. IOP reduction of group A (baseline IOP 17～24 mmHg) and groupB(baseline IOP 26-36 mmHg) was 30.1%, 26.3%, 25.6%,23.3%; and 17%, 21.5%. 15%, 10.9% at 1,3,6and 12 months, respectively. IOP reduction between two groups was significantly difference(P＜0.05). Conclusions Adverse effects of SLT for open angle glaucoma is a mild and temporary. Effect of lowing IOP isrelated to baseline pressure.