小口径人工血管植入术后再狭窄的研究进展

管腔再狭窄是导致外周人工血管植入术后失败的主要原因。过去已就提高人工血管的管壁性能和抗凝技术做了大量的研究，但是由于再狭窄导致人工血管，特别是口径小于5mm的人工血管长期通畅性问题依然没有满意的结果。因此本文就再狭窄的好发部位、组织学特征、发生机制以及包括损伤、炎症反应、顺应性、缝合方式等影响增生的一些因素进行综述。

Developmental Study of Restenosis of Small-Caliber Prosthetic Vascular Grafts

Restenosis is the major cause of prosthetic vascular graft failure after peripheral bypass surgery. Scho-(lars) have made many scientific researches to improve the properties of graft wall and the techniques of antithrombogenicity in the past years, yet the long term patency of prosthetic grafts especially small-caliber ones with the diameter less than 5 mm has not been satisfactory due to proliferative stenosis. This article reviews the predisposed restenosis incident sites, histological characters, mechanisms of proliferative stenosis of small-caliber grafts, and factors influencing hyperplasia, which include injury, stress, inflammation, compliance, suture techniques and so on.