口服降糖药临床应用分析

目的：分析常熟医院口服降糖药应用现状和趋势。方法：对2007—2009年我院口服降糖药应用品种、销售金额、用药频度（DDDs）和日均费用（DDC）进行回顾性分析。结果：3年口服降糖药销售金额占抗糖尿病药总金额48.12%;销售金额排序前3位的依次是：磺酰脲类、非磺酰脲类胰岛素促泌剂和α-糖苷酶抑制剂;DDDs排序前3位的依次是：磺酰脲类、双胍类和非磺酰脲类胰岛素促泌剂;3年中,阿卡波糖、瑞格列奈和格列吡嗪缓释片位列单品种销售金额前3位;格列吡嗪缓释片、二甲双胍和格列吡嗪普通片位列单品种DDDs的前3位;噻唑烷二酮类的DDC最高,双胍类最低。结论：我院口服降糖药用药合理且占主导地位.

Utilization of Oral Hypoglycemic Drugs

OBJECTIVE：To evaluate the status quo and tendency of utilization of oral hypoglycemic drugs in our hospital.METHODS：The use of oral hypoglycemic drugs used in our hospital during 2007-2009 was analyzed retrospectively in terms of drug varieties,consumption sum,DDDs and DDC etc.RESULTS：The consumption sum of oral hypoglycemic drugs represented 48.12% of that for all hypoglycemic drugs,leading the first 3 places were sulfonylurea,non-sulfonylurea insulin secretagogue drugs and α-glucosidase inhibitors.Leading the first 3 places on the list of DDDs were sulfonylurea,biguanides and non-sulfonylurea insulin secretagogue drugs.Over the 3 years,leading the top 3 on the consumption list of all the single kind of hypoglycemic drugs were acarbose,repaglinide and glipizide sustained release tablets,and leading the top 3 on the DDDs list for all the single hypoglycemic drugs were glipizide sustained release tablets,metformin and glipizide compressed tablets.The DDC of thiazolidinediones was the higtest and that of metformin was the lowest.CONCLUSION：The use of oral hypoglycemic drugs was rational and predominant in our hospital.