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47例普鲁卡因注射液不良反应文献分析
引用本文:黄跃洲,文世伟,吴逢波.47例普鲁卡因注射液不良反应文献分析[J].中国医院用药评价与分析,2010(10):944-945.
作者姓名:黄跃洲  文世伟  吴逢波
作者单位:四川大学华西医院药剂科,成都610041
摘    要:目的:分析普鲁卡因注射液所致不良反应的特点及相关因素,为药品不良反应的防治提供参考依据。方法:检索1986—2009年国内文献源普鲁卡因注射液的不良反应资料,并进行分析。结果:得到符合标准的病例47例,不良反应报告中男性多于女性;不良反应以全身性损害最多(18例,占38.30%),其次为皮肤及附件损害(9例,19.15%)、血液系统损害(7例,14.88%)、神经系统损害(5例,10.64%);不良反应较为严重。结论:临床应警惕普鲁卡因注射液的不良反应,应特别注意过敏性休克。

关 键 词:普鲁卡因注射液  不良反应  分析

Status of 47 Adverse Drug Reaction Cases of Procaine Injection on Documents
HUANG Yue-zhou,WEN Shi-wei,WU Feng-bo.Status of 47 Adverse Drug Reaction Cases of Procaine Injection on Documents[J].Evaluation and Analysis of Drug-Use in Hospital of China,2010(10):944-945.
Authors:HUANG Yue-zhou  WEN Shi-wei  WU Feng-bo
Institution:(Department of Pharmacy, West China Hospital of Sichuan University, Chengdu 610041, China)
Abstract:OBJECTIVE:To analyse the clinical features、correlation factors of ADR caused by Procaine Injection and provide beneficial references for preventing and curing the ADR.METHODS:To collect and analyse the cases of ADR caused by Procaine Injection from medical journals of 1986-2009.RESULTS:Men were more than women in 47 ADRs;Body as a whole-general disorders accounted for 38.30%,skin and its appendix lesions accounted for 19.15%,hematological system lesions accounted for 14.88%,hematological system lesions accounted for 10.64%.CONCLUSION:Clinic must be on guard against the adrs of Procaine Injection.
Keywords:Procaine injection  Adverse drug reaction  Analysis
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