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细茎银莲花的化学成分
引用本文:路金才,张 娜,单 娜,贾丽丽,樊 莉. 细茎银莲花的化学成分[J]. 中国药物化学杂志, 2009, 19(3): 209-211
作者姓名:路金才  张 娜  单 娜  贾丽丽  樊 莉
作者单位:沈阳药科大学 中药学院, 辽宁 沈阳110016
摘    要:
目的 对细茎银莲花(Anemone rossii Moore)根茎的化学成分进行初步研究。方法 细茎银莲花根茎以体积分数为75%的乙醇提取,提取物经系统溶剂萃取,对其氯仿萃取部分进行反复柱色谱分离,利用理化性质和波谱分析进行结构鉴定。 结果 从细茎银莲花根茎中分离得到7个已知化合物,分别为桦皮醇(1)、桦皮酸 (2)、齐墩果酸(3)、β-谷甾醇(4)、香豆素 (5)、4,7-二甲氧基-5-甲基香豆素 (6)、齐墩果酸-3-O-α-L-吡喃阿拉伯糖苷(7)。结论 所有化合物均为首次从细茎银莲花中分离得到。

关 键 词:细茎银莲花;化学成分;结构鉴定;色谱法
收稿时间:2008-07-10
修稿时间:2009-02-20

Chemical constituens of Anemone rossii Moore
LU Jin-cai,ZHANG Na,SHAN Na,JIA Li-li,FAN Li. Chemical constituens of Anemone rossii Moore[J]. Chinese Journal of Medicinal Chemistry, 2009, 19(3): 209-211
Authors:LU Jin-cai  ZHANG Na  SHAN Na  JIA Li-li  FAN Li
Affiliation:School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:
Aim To study the chemical constitutents from rhizome of Anemone rossii. Method The rhizome of the plant were extracted with 75% ethanol, the ethanol extract was extracted then with petroleum ether, chloroform, ethyl acetate and n-butanol respectively. The chloroform extraction was submitted to chromatography on silica gel column and seven compounds were isolated. Their structures were elucidated on the basis of physical-chemical method, spectral analysis and by comparison with certain authentic samples. Result The isolated compounds were identified as betulin (1), betulic acid (2), oleanolic acid (3), β-sitosterol (4), coumarin (5), 4,7-dimethoxyl-5-methyl-coumarin (6) , and oleanolic acid-3-O-α-L-arabinopyranoside (7)。Conclusion All these compounds are isolated from Anemone rossii Moore for the first time.
Keywords:Anemone rossii  chemical constituent  structural identification  chromatography
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