物理抗菌剂（洁悠神）防治急性放射性皮炎临床研究

目的应用具有长效物理抗菌功能的洁悠神喷洒于放射性皮炎发生区域的皮肤，观察洁悠神防治放射性皮炎的临床效果。方法将接受放射治疗过程中出现急性放射性皮炎的258例头颈部恶性肿瘤患者随机分为对照组122例和治疗组136例。治疗组采用洁悠神治疗，对照组采用涂抹烧伤膏和氢地油治疗，2组治疗时间均为6周。评价6周后治疗组与对照组2级及以上放射性皮炎的发生率。结果治疗组和对照组2级以上急性放射性皮炎的发生率分别为52．94％和65．57％，治疗组与对照组差异有显著性（X^2=4．24，P〈0．05）。结论洁悠神可预防继发感染、止痒止痛，促进创面愈合，能有效降低急性放射性皮炎的发生率。

Prevention and Treatment of Acute Radiodermatitis with JUC Physical Antimicrobial Spray Dressing

Objective To observe the clinical effects of JUC in preventing radiodermatitis by spraying the long - acting antibacterial material on the skin where radiodermatitis occurs. Methods 258 patients with malignant tumors in head and neck who got affected with acute radiodermatitis when receiving the radiotherapy were divided into control group and treatment group at random, with the control group including 122 patients and the other 136 patients. The patients in the treatment group were treated with JUC and those in control group were treated with burn ointment. The treatments of both groups lasted for 6 weeks. The incidence of radiodermatitis of Ⅱ degree as well as above Ⅱ degree of both groups was evaluated 6 weeks later. Results The incidences of acute radiodermatitis above the Ⅱ degree in treatment group and control group were 52.94% and 65.57% , respectively and there were significant differences between the two groups （ X^2 = 4.24, P 〈 0.05）. Conclusion JUC can prevent secondary infection, relieve itching and pain, promote wound healing and thus it can effectively reduce the incidence of acute radiodermatitis.