| 长春瑞滨联合草酸铂时辰化疗治疗晚期肺癌 |
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| 引用本文： | 杨兰平,黄汉生,陈洪,李建安,冯志强. 长春瑞滨联合草酸铂时辰化疗治疗晚期肺癌[J]. 临床肿瘤学杂志, 2004, 9(1): 11-13 |
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| 作者姓名： | 杨兰平 黄汉生 陈洪 李建安 冯志强 |
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| 作者单位： | 545005,广西柳州,柳州市肿瘤医院化疗科 |
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| 摘 要： | 目的：评价长春瑞滨(NVB)联合草酸铂(L-OHP)方案进行时辰化疗对晚期肺癌的治疗效果及其毒性反应。方法：2001年5月至2002年10月，对晚期肺癌32例(腺癌18例，鳞癌12例及小细胞肺癌2例)以NVB L-OHP时辰给药。至少两个周期评价疗效。结果：32例总有效率(CR PR)为46．9％，肺腺癌有效率为50％，鳞癌有效率为33．3％，小细胞肺癌有效率为100％。主要毒性反应为骨髓抑制和周围神经炎。结论：长春瑞滨与草酸铂联合方案进行时辰化疗对晚期肺癌有较好的治疗效果，毒性反应可以耐受。
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| 关 键 词： | 长春瑞滨 草酸铂 时辰化疗 治疗 晚期肺癌 NVB L-OHP 肿瘤 |
| 文章编号： | 1009-0460(2004)01-0011-03 |
| 修稿时间： | 2003-05-03 |
Time-chemotherapy with Navelbine plus Oxaliplatin regimen in advanced lung cancer |
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| YANG Lan-ping,HUANG Han-sheng,CHEN Hong,et al.. Time-chemotherapy with Navelbine plus Oxaliplatin regimen in advanced lung cancer[J]. Chinese Clinical Oncology, 2004, 9(1): 11-13 |
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| Authors: | YANG Lan-ping HUANG Han-sheng CHEN Hong et al. |
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| Affiliation: | YANG Lan-ping,HUANG Han-sheng,CHEN Hong,et al. Department of Chemotherapy,Liuzhou Tumor Hospital,Liuzhou 545005 |
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| Abstract: | Objective:The aim of this study was to evaluate the efficacy and toxicity of Time-chemotherapy with Navelbine (NVB)+Oxaliplatin (L-OHP) regimen in patients with advanced lung cancer.Methods:From May 2001 to October 2002, 32 patients of advanced lung cancer were enrolled in this study. Of them, 18 cases in adenocarcinoma; 12 cases in squamous cell carcinoma; 2 cases in SCLC. Give NVB+L-OHP on time. Every case was treated at least 2 cycles.Results:In 32 cases: The response rate (CR+PR) was 46 9%; 50% in adenocarcinoma, 33 3% in squamous cell carcinoma, and 100% in SCLC, respectively. The main toxicity was myelosuppression and peripheral neuritis.Conclusion:There was fairly efficacy and acceptable toxicity of Time-chemotherapy with NVB+L-OHP regimen in patients with advanced lung cancer. |
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| Keywords: | Navelbine Oxaliplatin Time-chemotherapy lung cancer |
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