手术前机械通气治疗婴儿重度肺动脉高压

目的探讨婴儿重度肺动脉高压术前机械通气支持治疗的可行性。方法2006年1月至2010年1月，我院对32例重度肺动脉高压患儿术前采取机械通气支持治疗24—72h，其中男18例，女14例；平均月龄（26±3）个月，平均体重（6．8±2．5）kg。结果应用呼吸机支持24h后，血流动力学改善，心率下降，平均动脉压上升，中心静脉压下降；动脉氧分压、动脉氧饱和度明显升高，乳酸及动脉二氧化碳分压明显下降，与机械通气前比较差异有统计学意义（P〈0．05）。术后1例死于多脏器功能衰竭。其余随访6个月～3年，均生存良好。结论术前机械通气支持治疗对提高婴儿重度肺动脉高压术后生存率、减少并发症有重要意义。

Treatment of mechanical ventilation support preoperative for grave pulmonary hypertension in infants

Objective To determermin the feasibility of the treatment of mechanical ventilation support preoperative for grave pulmonary hypertension in infants. Methods Thirty - two cases of pulmonary hypertension received mechanical ventilation support for 24 - 72 hours preoperative. There were 18 males and 14 females. All cases at the mean age of （ 6 ± 3 ） months and with the mean body weight （6.8 ± 2.5） kg. Results Hemodynamics and blood gas analysis index were improved at 24 hours after mechanical ventilation support, HR, CVP, Lac and PaCO2 were significantly decreased and at the sime time MAP, PaO2 and SaO2 were significantly increased （ P 〈 0.05）. One case died with multiple organ failure, all patients recovered well after following up 6 months to 3 years. Conclusions The treatment of mechanical ventilation support preoperative for grave pulmonary hypertension in infants to decrease postopertive complications and improve the success rate of the operation.