重症急性胰腺炎合并深部真菌感染易感因素剖析

目的：分析重症急性胰腺炎病人并发深部真菌感染的主要易感因素，并探讨其预防措施。方法：回顾性分析１９９６年１月～１９９９年１２月我院外科收治的１１９例重症急性胰腺炎病例。结果：重症急性胰腺炎病人并发真菌感染以念珠菌为主；病情严重程度、肠外营养和肠功能障碍≥５天对并发真菌感染有重要影响；预防用药可显著降低ＩＣＵ组真菌感染的发生率。结论：在本文比较的易感因素中，病人的病情严重程度、肠外营养、肠功能障碍≥５天等易感因素对重症急性胰腺炎合并真菌感染有显著影响。

Study on the Risk Factorsof Fungal Infection in Severe Acute Pancreatitis.

To investigate the risk factors of fungal infection in severe acute pancreatitis(SAP), and its preventive strategy. Methods: Retrospective analysis of 119 cases of SAP admitted from Janua- ry 1996 to December 1999. Results: Candida is the main strain of fungus in SAP. The risk factors of fungal infection were found to be:(1)Severity of disease; (2)Parenteral nutrition and enteral dysfunction more than five days; Prophylactic treatment can decrease the incidence of fungal infection in ICU. Conclusions: Severity, parenteral nutrition and enteral dysfunction more than five days are the main risk factors of fungal infection in SAP.