Bronchiolitis obliterans organizing pneumonia associated with sulfasalazine in a patient with rheumatoid arthritis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Bronchiolitis obliterans organizing pneumonia associated with sulfasalazine in a patient with rheumatoid arthritis

Authors:	Bahar?Uluba? author-information" > author-information__contact u-icon-before" > mailto:baharulubas@hotmail.com" title=" baharulubas@hotmail.com" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Gün?ah??ahin,Caner??zer,?zlem?Ayd?n,Eylem??zgür,Demir?Apayd?n

Affiliation:	(1) Department of Chest Disease, Faculty of Medicine, Mersin University, Koy-Tür (2) Sitesi, B(2) Blok, Daire 4, D.Tepe, 33320 Mersin, Turkey;(2) Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Mersin University, Mersin, Turkey;(3) Department of Radiology, Faculty of Medicine, Mersin University, Mersin, Turkey;(4) Department of Pathology, Faculty of Medicine, Mersin University, Mersin, Turkey

Abstract:	Pulmonary toxicity and blood dyscrasias are rare side effects of sulfasalazine. Pulmonary pathology is variable, the most common being eosinophilic pneumonia with peripheral eosinophilia, and interstitial inflammation with or without fibrosis. We here present the case of a 68-year-old female patient treated for 6 months with sulfasalazine for rheumatoid arthritis. On laboratory examination, eosinophil count was 97×10³ mm³. Thorocoscopic biopsy was performed . Histopathologic diagnosis was bronchiolitis obliterans organizing pneumonia (BOOP). This is the first case in the literature to present with sulfasalazine-induced BOOP in a patient with seronegative RA.Abbreviations BOOP Bronchiolitis obliterans organizing pneumonia - DMARS Disease-modifying antirheumatic drugs - RA Rheumatoid arthritis

Keywords:	Bronchiolitis obliterans organizing pneumonia
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