| Th17细胞／Treg细胞的分化、功能及在支气管哮喘中的作用 |
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| 引用本文： | 张雪雅,张维溪,李昌崇. Th17细胞／Treg细胞的分化、功能及在支气管哮喘中的作用[J]. 国际呼吸杂志, 2014, 0(5): 364-366 |
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| 作者姓名： | 张雪雅 张维溪 李昌崇 |
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| 作者单位： | 温州医科大学附属育英儿童医院呼吸科,325027 |
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| 基金项目： | 国家自然科学基金资助项目（81100015） |
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| 摘 要： | Thl7可特异性分泌1L-17A、IL-17F和IL-22，参与调控胞外细菌和真菌感染及多种自身免疫性疾病。Treg具有免疫抑制作用，主要机制是依赖于细胞间或非细胞间的相互作用。Foxp3在Treg分化和维持功能中发挥重要作用。在此，将对Thl7细胞／Treg细胞的分化、功能及其支气管哮喘中的作用作一综述。
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| 关 键 词： | Thl7细胞 Treg细胞 分化 哮喘 |
Differentiation,function of Thl7 Cells/Treg cells and role in bronchial asthma |
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| Zhang Xueya,Zhang Weixi,Li Changchong. Differentiation,function of Thl7 Cells/Treg cells and role in bronchial asthma[J]. International Journal of Respiration, 2014, 0(5): 364-366 |
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| Authors: | Zhang Xueya Zhang Weixi Li Changchong |
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| Affiliation: | . Department of Respiratory Diseases , Yuying Childrenls Hospital Affiliated to Wenzhou Medical University, Wenzhou 325027, China |
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| Abstract: | Thl7 cells specificly produce cytokines such as IL-17A, IL-17F and IL-22. Thl7 is involved in the regulation of extracellular bacterial, fungal infections and autoimmune diseases. Treg cells suppress immune responses through cell-cell or non-cell interaction. Foxp3 plays a great role in differentiation and function of Treg cells. Here, we review the progress of the differentiation, function of Thl7 cells and Treg cells,as well as the role of Thl7 Cells and Treg cells in bronchial asthma. |
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| Keywords: | Thl7 cells Treg cells Differentiation Asthma |
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