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获得性免疫缺陷综合征与炎症的抗逆转录病毒治疗进展
引用本文:董耘婷,;卢洪洲.获得性免疫缺陷综合征与炎症的抗逆转录病毒治疗进展[J].世界临床药物,2014(8):449-452.
作者姓名:董耘婷  ;卢洪洲
作者单位:[1]上海市(复旦大学附属)公共卫生临床中心,上海201508; [2]复旦大学附属华山医院感染科,上海200040
基金项目:国家“十二五”重大新药创制:抗艾滋病病毒新药临床评价研究技术平台建设(2012ZX09303013).
摘    要:抗逆转录病毒治疗(ART)可抑制人免疫缺陷病毒(HIV)的复制,减少机会性感染的发生,但不能完全抑制HIV引起的炎症和免疫激活,残留的炎症导致一系列疾病(HIV并存病)。本文简要综述近几年来国内外HIV与炎症的ART进展。

关 键 词:人免疫缺陷病毒(HIV)  炎症  抗逆转录病毒治疗(ART)

Progress on anti-retroviral therapy for acquired immunodeficiency syndrome and inflammation
Institution:DONG Yun-ting, LU Hong-zhou (1. Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508; 2. Department of lnfectious Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China)
Abstract:Anti-retroviral therapy (ART) can inhibit the replication of human immunodeficiency virus (HIV) infected patients and reduce opportunistic infections. However, ART does not completely control inflammation and immunoactivation caused by HIV. This review describes the research progress on the correlation of HIV with inflammation and HIV complication.
Keywords:human immunodeflciency virus(HIV)  inflammation  anti-retroviral therapy(ART)
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