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长期应用依那普利对高血压病患者左室结构及功能影响
引用本文:于波,胡健,梁晓光,李淑芹,曾定尹. 长期应用依那普利对高血压病患者左室结构及功能影响[J]. 临床心血管病杂志, 1997, 0(2)
作者姓名:于波  胡健  梁晓光  李淑芹  曾定尹
作者单位:中国医科大学第一医院循环内科!沈阳110001
摘    要:
观察了28例Ⅱ期高血压病患者平均口服依那普利平均22个月后左室结构及功能改变。结果显示:用药后血压降低总有效率为89.3%,心率无变化。用药后空间隔、左室后壁及左定重量指数均明显下降(P<0.05),A峰速度及A/E比值明显下降,E峰速度明显增高(P<0.05)。提示:依那曾利长期治疗可有效降压,并同时逆转左室肥厚,改善左室舒张功能。

关 键 词:依那普利  心功能  左室肥厚

Long-term effects of enalapril on left ventricular hypertrophy and left ventricular function in hypertensive patients
Yu Bo, Hu Jiang, Liang Xiaoguang, et al. Long-term effects of enalapril on left ventricular hypertrophy and left ventricular function in hypertensive patients[J]. Journal of Clinical Cardiology, 1997, 0(2)
Authors:Yu Bo   Hu Jiang   Liang Xiaoguang   et al
Abstract:
28 hypertensive patients were given enalapril 5 ~10mg for an average of 22 months. The blood pressure,left ventricular structure and cardiac function were observed. The re sults showed that SBP and DBP decreased (P<0.01),HR didn't change (P>0.05), LVMI,IVS,PWT became thiner (P <0.05), PEV increased,PAV, A/E ratio decreased (P <0.05). The re sults demonstrated that enalapril had good effects for hypertension,it could decrease blood pres sure,regress left ventricular hypertrophy and improve cardiac function.
Keywords:Enalapril Cardiac function Left ventricular hypertrophy
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