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Lack of connection between the atria and the peripheral conduction system in a case of corrected transposition with congenital atrioventricular block |
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| Authors: | Saroja Bharati Carolyn M. McCue Jon B. Tingelstad Michael Mantakas Fergus Shiel Maurice Lev |
| Affiliation: | 1. From the Congenital Heart Disease Research and Training Center, Hektoen Institute for Medical Research, Chicago, Illinois, USA;2. From the Department of Pathology, Northwestern University Medical School, Chicago, Illinois, USA;3. From the Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA;4. From the Chicago Medical School, University of Health Sciences, Chicago, Illinois, USA;5. From the Stritch School of Medicine, Loyola University, Chicago, Illinois, USA;6. From the Section of Cardiology, Department of Medicine and the Department of Pathology, Abraham Lincoln School of Medicine, University of Illinois, Chicago, Illinois, USA;7. From the Departments of Pediatrics, Medicine and Pathology, Rush Medical College, Chicago, Illinois, USA;8. From the Division of Pediatrie Cardiology, Department of Pediatrics and Department of Pathology, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia, USA |
| Abstract: | This is the first documented histologic study of the heart of a patient with corrected transposition of the great vessels and congenital atrioventricular (A–V) block with no connection between the atria and an anterior type of peripheral conduction system. Musculature in the superior (anterior) walls of both atria was absent, as was the anterior A–V node. The peripheral conduction system began with the bundle of His. In place of the absent atrial musculature, fibrosis and calcification were present. The relation of laboratory evidence of connective tissue dyscrasia in the mother to the congenital A–V block in the child is discussed. |
| Keywords: | Address for reprints: Maurice Lev MD 637 South Wood Street Chicago Illinois 60612. |
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