无创正压通气对轻中度哮喘急性发作病人的治疗评估

目的探讨轻中度哮喘急性发作病人应用无创正压通气(NPPV)的临床疗效。方法32例支气管哮喘急性发作患者,随机分为治疗组和对照组,各16例在抗感染、平喘、激素等常规治疗的基础上,给予NPPV。多参数监护仪持续监测呼吸频率(RR)、心率(HR),血氧饱和度(SaO2),并在通气前、通气后30min,1、2h分别取其具体数值进行统计。结果治疗后30min、1h:RR、HR、SaO2的两组间差异均表现出显著性意义(P<0.05)。治疗后2h:两组的RR、HR、SaO2在监测数据上虽然有明的差异,但无统计学意义(P>0.05)。结论NPPV能迅速改善轻中度哮喘急性发作时的缺氧状态、缓解呼吸肌疲劳、临床症状明显缓解,患者耐受性好、乐于接受。

Clinical evaluation of noninvasive positive pressure ventilation in the treatment of acute asthma

Objective To evaluate the effect of noninvasive positive pressure ventilation(NPPV)in treating asthma during an acute attack.Methods A randomized,placebo-controlled and prospective study was conducted,Thirty-two cases were divided into 2 groups(an experimental group and a placebo-controlled group)with 16 cases in each group.Being maintained on routine treatment,the experimental group was also treated with NPPV,whereas the placebo-controlled group was assigned to receive only routine treatment.Results There were significant differences between the experimental group and the placebo-controlled group in heart rate and respiratory rate.Conclusion It was beneficial for the patients with asthma during acute attack to be treated with NPPV,though those patients suffer from mild or medium asthma.