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| 栀子指纹图谱及不同生长期西红花苷和栀子苷含量的研究 | |
| 引用本文： | 石凤鸣,王文君,陈雏,蔡乐,张浩,陈阳.栀子指纹图谱及不同生长期西红花苷和栀子苷含量的研究[J].时珍国医国药,2011,22(8):1874-1876. |
| 作者姓名： | 石凤鸣 王文君 陈雏 蔡乐 张浩 陈阳 |
| 作者单位： | 1. 遵义医学院第五附属(珠海)医院,广东珠海,519000 2. 遵义医学院珠海校区,广东珠海,519041 3. 四川大学华西药学院,四川成都,610041 |
| 基金项目： | 遵义医学院博士启动基金，贵州省国际合作项目基金，贵州省科学技术基金 |
| 摘 要： | 目的研究不同产地栀子指纹图谱及不同生长期西红花总苷和栀子苷含量。方法采用高效液相色谱法建立了全国不同产地栀子的指纹图谱,并测定了不同产地及同一产地不同采收期药材西红花苷和栀子苷的含量。结果 各地栀子药材与对照指纹图谱的相似度分别为0.980,0.992,0.978,0.989,0.948,0.991,0.986,0.996,0.993,0.965。不同产地栀子的栀子苷平均含量为4.11%;西红花总苷含量最低为1.41%,最高达3.08%,相差一倍以上。而不同采收期药材测定结果显示,西红花总苷含量从8月中旬的0.009%增加到11月中旬的1.32%,之后趋于下降。而栀子苷含量则在刚结果的8月中旬最高,之后逐渐下降。结论 各产地栀子药材表现较高的相似度,说明栀子药材所含化学成分随产地变化小。西红花苷含量随着栀子的成熟而显著增加,但过度熟透的果实也不利于西红花苷的稳定。而栀子苷主要在果实形成后的短期内生成,此后由于果实的生长,其浓度反而下降。 |
| 关 键 词： | 栀子 西红花苷 栀子苷 指纹图谱 |
Fingerprints of Gardenia Fruits and the Conteut Changes of Crocin and Geniposide in Different Collection Periods |
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| SHI Feng-ming,WANG Wen-jun,CHEN Chu,CAI Le,ZHANG Hao,CHEN Yang.Fingerprints of Gardenia Fruits and the Conteut Changes of Crocin and Geniposide in Different Collection Periods[J].Lishizhen Medicine and Materia Medica Research,2011,22(8):1874-1876. | |
| Authors: | SHI Feng-ming WANG Wen-jun CHEN Chu CAI Le ZHANG Hao CHEN Yang |
| Institution: | SHI Feng-ming1,WANG Wen-jun2,CHEN Chu3,CAI Le3,ZHANG Hao3,CHEN Yang2*(1.The Fifth Afficiated Hospital of Zunyi Medical College,Zhuhai,Guangdong 519000,China,2.Department of Chemistry,Zunyi Medical College Zhuhai Campus,Zhuhai 519041,3.West China School of Pharmacology,Sichuan University,Chengdu 610041,China) |
| Abstract: | Objective To investigate HPLC fingerprints,total crocin and geniposide contents of gardenia fruits.Methods An HPLC method for fingerprint of gardenia fruits was employed to evaluate the similarities of 10 samples which were collected from different areas.And then,total crocin and geniposide contents of herbs from different areas,as well as cultivated in different collection periods from the same area,were determined using the same HPLC method.Results Similarities of various cultivars were calculated to be 0... |
| Keywords: | Gardenia Crocin Geniposide Fingerprint |
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