代谢综合征在急性冠脉综合征患者中的流行特点分析

目的：探讨代谢综合征（MetS）及其组分在急性冠脉综合征（ACS）患者中的流行特点。方法：连续入选诊断为ACS住院患者387例，分析MetS及各组分在ACS患者中的检出率及其流行特点，同时进行MetS组分在MetS与非MetS组间流行特点比较。结果：387例ACS患者平均年龄（54.21±11.21）岁，228例（占58.9%）为MetS患者，其中ST段抬高心肌梗死（STEMI）占52.6%，非ST段抬高急性冠脉综合征（NSTE-ACS）占47.4%，两组之间差异无统计学意义（P＞0.05）。ACS合并MetS人群中最常见的代谢紊乱为低高密度脂蛋白胆固醇（HDL-c）血症（占87.1%）和糖代谢异常（占81.2%）。91.3%的患者合并2种或以上的代谢紊乱，仅有8.0%合并1种代谢紊乱。最常见的组合形式为高甘油三酯＋低HDL-c＋糖代谢异常（占54.7%）和高甘油三酯＋腹型肥胖＋低HDL-c＋高血压（占61.0%）。结论：ACS患者中MetS患病率极高。无论是否患有糖尿病，低HDL-c均为ACS患者最常见的代谢紊乱。

Analysis of epidemic characteristics of metabolic syndrome in acute coronary syndrome patients

Objective： To explore the prevalence of metabolic syndrome and the combination of its com-ponents in a cohort of patients with acute coronary syndrome.Methods： Clinical histories of 387 inpatients with acute coronary syndrome were selected. They were categorized according to the speciifc criteria stated in the latest joint statement for the global deifnition of MS.Results： The metabolic syndrome presented in 58.9%. The most prevalent component was low HDL-c （87.1%） and impaired fasting glucose （81.2%）. The most frequent combination of components was elevated triglycerides＋lower HDL-c＋impaired fasting glucose （54.7%） and elevated triglycerides＋lower HDL-c＋abdominal visceral obesity＋hypertension.Conclusion： The metabolic syn-drome has a high prevalence in patients with acute coronary syndrome. No matter with or without diabetes, the most frequent components is low HDL-c levels.