出血性放射性膀胱炎经膀胱灌注透明质酸钠的疗效分析

目的：探讨膀胱灌注透明质酸钠治疗出血性放射性膀胱炎的疗效。方法：经膀胱灌注透明质酸钠治疗出血性放射性膀胱炎32例（透明质酸钠治疗组），对比同时期20例常规保守止血治疗患者（保守治疗组）。治疗1年后，以尿常规检测红细胞下降到＋/HP为有效。结果：透明质酸钠治疗组28例有效，有效率为87.5%，17例伴尿路刺激症状患者症状明显改善；保守治疗组8例有效，有效率为40%。结论：膀胱灌注透明质酸钠治疗出血性放射性膀胱炎疗效显著，操作简单，无不良反应，重复性强，尤其适用于伴有尿路刺激症状的患者。对于重度出血性膀胱炎患者，建议先行经尿道膀胱内电灼止血后，再行透明质酸钠灌注治疗。

Analysis on the curative effect of bladder perfusion sodium hyaluronate in hemorrhagic radiation cystitis

Objective： To explore the curative effect of treatment with bladder perfusion sodium hyaluro-nate in hemorrhagic radiation cystitis.Methods： Compared with 20 patients with routine conservative hemostatic treatment （Conservative treatment group）, bladder perfusion hyaluronic acid sodium was used for the treatment of hemorrhagic radiation cystitis in 32 cases （Hyaluronic acid sodium treatment group）. Red blood cells decreased to ＋/HP was effective in the routine urine test, after one year’s treatment.Results： In sodium hyaluronate infu-sion group, 28 cases were effective, and its rate was 87.5%, 17 cases with urinary irritation symptoms improved signiifcantly. 8 cases of conservative treatment group were effective. and its rate was 40%.Conclusion： Bladder perfusion hyaluronic acid sodium for the treatment of hemorrhagic radiation cystitis curative effect is distinct, the operation is simple, non-toxic side effects, strong repeatability, particularly suitable for patients with urinary ir-ritation symptoms. For patients with severe hemorrhagic cystitis, Transurethral intravesical electrocauterization is ifrstly performed to stop bleeding, then start treatment with sodium hyaluronate infusion.