微血管性心绞痛发病机制的研究进展

微血管性心绞痛是指冠状动脉造影正常的患者,在除外其他特殊心脏疾病后,存在的有心肌缺血或微循环病变证据支持的胸痛.微血管性心绞痛的发病机制目前仍不清楚,有多种因素共同参与,包括冠状动脉微循环功能不全、心脏自主神经功能失调、雌激素水平不足、冠状动脉慢血流综合征、血管痉挛等.现就微血管性心绞痛发病机制的研究进展进行探讨.

Advances in Pathogenesis of Microvascular Angina

Microvascular angina（MVA） is referred to angina like chest pain which is supported by evidence of myocardial ischemia or microcirculation abnormalities in the absence of any cardiac or systemic disease in patients who have normal coronary angiograms. The pathogenesis of MVA is still unclear. Various factors are considered to be involved, including coronary microvascular dysfunction, cardiac autonomic nervous system imbalance, estrogen deficiency, coronary slow flow phenomenon and vasospasm. The advances in the pathogenesis of MVA will be discussed following.